Case #

Age, gender

Suspected

for

Contact with asbestos, fiber-year count

Macroscopic features

Histology

Asbestos bodies/ asbestos fibers [per gram lung tissue]

Final diagnosis

1

76, M

Silicosis

No

See (Figure 1)

See (Figure 1)

N.D.

Papillary renal carcinoma

2

71, M

Silicosis

No

Pleural adhesions with mediastinum, diaphragm, and chest wall; small white nodule within lung tissue

Disseminated tumor cells in the lower lobe. Lymphangiosis. Hemangiosis. lymph node metastases

N.D.

Adeno-carcinoma right lung,

Neuroendocrine tumor left lung

3

65, M

Asbestosis

Mesothelioma

Yes, 14.5

Pleura plaques left side, pleural thickening + adhesions to chest wall and right sided mediastinum

Alveolar carcinoma. Lymphangiosis.

Hemangiosis. LN metastases: carina, paratracheal. Right sided pleural infiltration

N.D.

Adeno-carcinoma

right lung

4

85, M

Asbestosis/

Mesothelioma

Yes

Pleural thickening

Non-differentiated adenocarcinoma of the lung with large-cell neuroendocrine differentiation; diffuse pleural metastasis

30/10

Adeno-carcinoma

5

67, M

Asbestosis/

Mesothelioma

(Yes)

Pleura plaques, pleural thickening

Non-differentiated keratinizing squamous cell carcinoma

1240/200

Squamous lung carcinoma

6

77, M

Asbestosis/

Mesothelioma

Yes

Universal thickening of the pleura including interlobular septa

Cuboid epithelial cells; hyperchromatic nuclei.

Lymphangiosis. Tumor extends in right lung hilar and tracheal bifurcation.

880/40

Pleural mesothelioma

7

81, M

Asbestosis/

Mesothelioma

Yes

pleural thickening left side

solid growing malignant tumor with pleomorphic nuclei, fine-granulated chromatin, prominent nucleoli. Multiple mitotic figures

110/100

Pleural mesothelioma

8

88, M

Asbestosis/

Mesothelioma

Yes

Pleural plaques, pleural thickening on the right side, infiltrating in the lung, thorax wall, diaphragm

Tumor of the right pleura, infiltrating all lung lobes, and the diaphragm. Lymphangiosis of the right pleura

4400/

Pleural mesothelioma