Table 2: Summarizes the nanoparticles modified platforms with specific oncogenes to detect HPV with their high sensitivity.

­­S.No.

Gene Specific for HPV

Nanocomposite and electrodes used

Detection limit

Sensitivity

Linear Range

Reference

1.

HPV16

platinum surface/polyaniline-multiwalled carbon nanotube composite

 

490pM

 

1.75 ± 0.2 μA nM-1

10nM-50nM

 

[47]

2.

HPV16

4-aminothiophenol, on a polymethylmethacrylate substrate with a gold nanolayer

 

NR

NR

NR

[48]

3.

HPV16 and HPV18

 

graphene/Au nanorod/polythionine

 

4.03×10-14 mol/L

NR

1.0×10-13

 

[49]

4.

HPV16 and HPV18

 

acpcPNA probe/gold deposited SPCE

 

0.1-1000nM

 

NR

0.5nM-100nM

 

[50]

5.

HPV 16

porous reduced graphene oxide/Molybdenum disulfide

1.75pM

2.35-0.76 (ng mL-1)

3.5pM-35.3pM

[45]

6.

HPV16

graphene-polyaniline (G-PANI)

2.3nM

NR

10nM-200nM

[51]

7.

HPV 16 and HPV 18

CysSso7d/Au NP (gold nanoparticles)

1.00ng mL-1

 

85.7%/100.0% and 85.7%/91.7%

to 1.00×103 ng mL-1

 

[52]

8.

HPV16

 

gold nanosheets

 

0.15pM

 

NR

1pM-1μM

 

[53]

9.

HPV16

 

titanium dioxide nanoparticles

 0.1fM

40x 10-4 (AM-1)

10fM-10μM

[54]

10

HPV16

 

AuNTs-PC

1fM

0.01pM

0.01pM to 1μM

[55]

11.

HPV18

 

Ti3C2 nanosheets

100pM

NR

1.0nM and 50nM

[56]

12.

HPV18

 

rGO and MWCNTs

0.05fM

NR

0.01fM to 0.01nM

[57]

*NR= Not reported