Cell type

CIBERSORT fraction in % of all infiltrating immune cells

(mean± SD)

de novo AML                               Relapsed AML                                           P value

B cells naive

0.042±0.060

0.069±0.077

0.111

B cells memory

0.017±0.033

0.015±0.023

0.741

Plasma cells

0.036±0.043

0.018±0.025

0.002

T cells CD8

0.021±0.033

0.034±0.053

0.245

T cells CD4 naive

0.060±0.071

0.029±0.047

0.006

T cells CD4 memory resting

0.019±0.044

0.035±0.053

0.150

T cells CD4 memory activated

0.005±0.011

0.009±0.021

0.303

T cells follicular helper

0.003±0.010

0.009±0.017

0.124

T cells regulatory (Tregs)

0.003±0.017

0.007±0.023

0.443

T cells gamma delta

0.026±0.033

0.030±0.062

0.747

NK cells resting

0.076±0.100

0.107±0.121

0.229

NK cells activated

0.029±0.054

0.034±0.060

0.711

Monocytes

0.370±0.252

0.301±0.210

0.136

Macrophages M0

0.009±0.019

0.011±0.037

0.801

Macrophages M1

0.017±0.045

0.018±0.054

0.890

Macrophages M2

0.015±0.029

0.005±0.013

0.002

Dendritic cells resting

0.002±0.001

0.001±0.003

0.788

Dendritic cells activated

0.008±0.027

0.010±0.027

0.749

Mast cells resting

0.167±0.187

0.122±0.180

0.245

Mast cells activated

0.037±0.090

0.047±0.109

0.684

Eosinophils

0.012±0.037

0.001±0.002

<0.001

Neutrophils

0.025±0.054

0.088±0.144

0.045