Variables

Univariate analysis

p-value

Multivariate analysis

p-value

HR

95%Cl of HR

HR

95%Cl of HR

Age (<60 vs ≥60) (years)

1.005

0.987-1.023

0.591

1.013

0.993-1.033

0.201

Gender (Male vs Female)

0.780

0.487-1.249

0.301

1.094

0.644-1.861

0.738

Grade (G1+G2 vs G3+G4)

1.017

0.746-1.387

0.914

1.962

0.687-1.347

0.823

Stage (I-II vs III-IV)

1.865

1.456-2.388

8.07e-07***

1.001

0.368-3.722

0.999

T1+T2 vs T3+T4

1.804

1.434-2.270

4.73e-07***

1.562

0.633-3.858

0.333

M1 vs M0

3.850

1.207-12.281

0.023*

2.622

0.655-10.497

0.173

N0 + N1 vs N2 + N3

2.022

0.494-8.276

0.328

1.413

0.218-9.092

0.716

ANLN (low expression vs high expression)

1.135

1.082-1.200

1.41e-07***

1.698

1.322-2.181

3.34e-05***