Characteristics

Univariate analysis (DFS)

Multivariate analysis (DFS)

HR

95% CI

p-value

HR

95% CI

p-value

Metastatic status at diagnosis

6.436

2.357-17.573

< 0.001

1.112

0.260-4.905

0.871

Risk group

4.185

2.199-7.963

< 0.001

2.607

1.103-6.162

0.029

Upfront surgery

3.385

1.516-7.560

0.003

2.101

0.773-5.710

0.146

Stage

2.264

1.315-3.898

0.003

1.054

0.458-2.427

0.901

Histopathological subtypes

0.708

0.612-0.820

< 0.001

0.740

0.623-0.879

0.001

ECGO-PS

1.516

0.975-2.357

0.065

Characteristics

Univariate analysis (OS)

Multivariate analysis (OS)

HR

95% CI

p-value

HR

95% CI

p-value

Metastatic status at diagnosis

17.477

3.836-79.626

< 0.001

8.825

1.144-68.064

0.037

Risk group

3.111

1.550-6.245

< 0.001

0.820

0.332-2.028

0.668

Upfront surgery

6.633

2.325-18.920

< 0.001

3.706

1.069-12.853

0.039

Stage

3.018

1.513-6.022

0.002

0.874

0.290-2.630

0.811

Histopathological subtypes

0.723

0.612-0.854

< 0.001

0.757

0.613-0.934

0.009

ECGO-PS

1.720

1.014-2.917

0.044

1.229

0.649-2.329

0.527