Variables

Univariate analysis

p-value

Multivariate analysis

p-value

HR

95%Cl of HR

HR

95%Cl of HR

Age (<60 vs ≥60) (years)

1.005

0.987-1.023

0.591

1.010

0.990-1.031

0.311

Gender (Male vs Female)

0.780

0.487-1.249

0.301

0.999

0.589-1.693

0.996

Grade (G1+G2 vs G3+G4)

1.017

0.746-1.387

0.914

1.070

0.763-1.501

0.694

Stage (I-II vs III-IV)

1.865

1.456-2.388

8.07e-07***

1.205

0.450-3.226

0.710

T1+T2 vs T3+T4

1.804

1.434-2.270

4.73e-07***

1.416

0.585-3.431

0.441

M1 vs M0

3.850

1.207-12.281

0.023*

1.825

0.480-6.934

0.377

N0 + N1 vs N2 + N3

2.022

0.494-8.276

0.328

1.966

0.295-13.115

0.485

HMMR (low expression vs high expression)

1.153

1.090-1.220

7.51e-07***

1.154

1.080-1.233

2.16e-05***