Abiraterone

Cabazitaxel

Docetaxel

Enzalutamide

Therapy line (n in line)

N

Median
95% CI

r-Mean

N

Median
95% CI

r-Mean

N

Median 95% CI

r-Mean

N

Median
95% CI

r-Mean

1st line

(n=447)

216

8.3
[6.9; 0.1]

5.1

2

1.2
[0.9; NA]

1.2

169

3.5
[3.0; 4.1]

3.6

60

3.7
[10.4; 5.6]

4.5

2nd line

(n=216)

106

7.4
[4.9; 8.8]

4.7

13

4.8
[3.5; NA]

4.5

50

3
[2.1; 4.3]

3.0

47

2.9
[5.7; 1.6]

3.9

3rd line

(n=105)

37

3.3
[2.3; 6.9]

3.9

13

2.8
[1.4; NA]

3.3

14

3.7
[2.6; NA]

3.4

41

2.9
[7.5; 0.5]

4.3

4th line

(n=52)

16

3.7
[2.9; NA]

3.8

8

2.1
[2.1; NA]

2.5

6

4.9
 [1.4; NA]

4.2

22

1.8
[10.2; 0.2]

3.7