Table 1: Prognostic factors in patients with refractory/relapsed acute myeloid leukemia (n=45).

Parameter

n

Median survival time (Months)

2 year-OS(%)

Chi-square

P value

Age

 

 

 

 

9.178

0.012

<60 years

≥60 years

28

13±4.43

36.4±0.96

 

17

3±0.68

0

Gender

 

 

 

 

0.219

0.718

Male

Female

24

8.00±3.262

18.9±1.08

 

 

21

9±4.577

23.8±9.3

 

 

Performance status

 

 

 

2.891

0.189

0-1

2-3

25

6±3.37

38.5±10.4

 

 

20

9±2.91

7.1±6.5

 

 

Type of AML

 

 

 

3.375

0.403

Primary

Secondary

42

10±2.92

49±7.9

 

 

3

3±1.63

0

 

 

Cytogenetic abnormality

 

 

 

0.597

0.478

Favorable

Intermediate

Poor

Missing

4

9±1.10

-

 

 

11

10±3.60

-

 

 

11

7±3.56

-

 

 

19

6±8.49

27.8±10.6

 

 

CR duration

 

 

 

3.241

0.198

<6 months

19

4±1.36

18.9±9.4

 

 

6-12 months

9

-

-

 

 

>12months

17

13±3.54

10.8±9.6

 

 

HSCT before relapse

 

 

 

0.225

0.635

Yes

No

5

7±2.18

4.34

 

 

40

16±8.22

47±8

 

 

HSCT after relapse

 

 

 

15.236

<0.0001

Yes

no

15

-

6.6±5.7

 

 

30

4±1.39

55.1±13.9