Table 2: Summary of the common histologic findings for the main subtypes of primary cutaneous B-cell lymphoma.
|
|
PCDLBCL-LT |
PCFCL |
PCMZL |
|
Histology |
Diffuse non-epidermotropic infiltrates; commonly sheets of monotonous large rounded cells; many mitotic figures are common |
Nodular or diffuse non-epidermotropic infiltrates consisting of monotonous follicular cells |
Nodular or diffuse non-epidermotropic infiltrates |
|
Cyto-pathology |
Centroblasts and immunoblasts; small B-cells and reactive T-cells are rare |
Centrocytes with centroblasts and immunoblasts; admixed with follicular dentritic cells and numerous reactive T-cells; follicular architecture often ill-defined |
Lymphocytes, marginal zone B-cells, centrocyte-like cells, plasma cells, centroblasts, immunoblasts, and lymphoplasmacytic cells; reactive T-cells and germinal centers |
PCDLBCL-LT: primary cutaneous diffuse large B cell lymphoma- leg type; PCFCL: primary cutaneous follicle center lymphoma; PCMZL: primary cutaneous marginal zone lymphoma [3, 4].