Table 2: Correlation analysis between the biomarkers. Data are presented for all tumors and stratified by p16 status. Numbers in bold represent significant correlations.

 

p16

CD44

C-MET

EGFR

MTOR

CD44

all

p16+

p16-

 

0.28  (p=0.004)

 

 

 

 

C-MET

all

p16+

p16-

 

-0.08 (p=0.37)

 

0.05 (p=0.61)

0.10 (p=0.49)

0.00 (p=0.997)

 

 

 

EGFR

all

p16+

p16-

 

-0.17 (p=0.08)

 

0.02 (p=0.85)

-0.20 (p=0.15)

0.11 (p=0.43)

 

-0.03 (p=0.79)

-0.02 (p=0.88)

-0.044 (p=0.75)

 

 

MTOR

all

p16+

p16-

 

-0.12 (p=0.22)

 

0.37 (p<0.001)

0.32 (p=0.02)

0.39 (p=0.004)

 

0.24 (p=0.01)

0.16 (p=0.28)

0.03 (p=0.03)

 

-0.11 (p=0.23)

-0.24 (p=0.08)

-0.05 (p=0.74)

 

GLUT1

all

p16+

p16-

 

-0.12 (p=0.23)

 

0.33 (p=0.001)

0.17 (p=0.21)

0.41 (p=0.005)

 

0.05 (p=0.62)

0.08 (p=0.55)

0.01 (p=0.95)

 

0.09 (p=0.36)

-0.04 (p=0.77)

0.16 (p=0.28)

 

0.30 (p=0.002)

0.30 (p=0.03)

0.28 (p=0.0.063)