Table 2: Keratins expression in non-cancerous breast tissue, where “-” represents negative staining, “+” represents weak positive staining, “++” represents positive staining and “+++” represents strongly positive staining.

 

Normal tissue

Malignant tissue

Neutral-basic or acidic

Acidic

Neutral-Basic

Acidic

Neutral-Basic

Type of keratin

19

5

19

5

Breast

Complex epithelia

Basal and

myoepithelial cells

++

+++

++

-

Luminal cells

+++

+

++

-