Variable

Univariate analysis

Multivariate analysis

RR

95% CI

p value*

RR

95% CI

p  value

Age (years)

≤ 70.0

1.00

Reference

> 70.0

2.25

0.83-6.06

0.109

PSA

≤ 8.1 ng/mL

1.00

Reference

1.00

Reference

> 8.1 ng/mL

2.85

1.12-7.26

0.027

2.72

0.99-7.49

0.052

AJCC Grade

1-3

1.00

Reference

4-5

2.67

0.90-7.87

0.074

Clinical stage

cT1-2

1.00

Reference

0.104

cT3-4

1.97

0.87-4.48

Pathological stage

pT1-2

1.00

Reference

pT3-4

4.13

1.53-11.15

0.005

Radical surgery

yes

0.51

0.23-1.17

0.111

0.12

0.03 – 0.56

0.007

no

1.00

Reference

1.00

Reference

Hist-pat surgical margines

negative

0.90

0.39-2.07

0.817

0.09

0.02 – 0.48

0.005

positive

1.00

Reference

1.00

Reference

Seminal vesicle(s) invasion

negative

1.00

Reference

positive

2.57

1.09-6.06

0.013

Adjuvant treatment

no

1.00

Reference

1.00

Reference

yes

2.77

1.17-6.55

0.020

3.43

1.26-9.35

0.016

Ki-67LI

≤ 12.8 %

1.00

Reference

> 12.8 %

2.86

1.12-7.25

0.027

GLUT-1LI

≤ 16.0 %

1.00

Reference

> 16.0 %

2.40

0.89-6.47

0.083

VEGF LI

≤ 16.0 %

1.00

Reference

> 16.0 %

0.61

0.25-1.50

0.282

MVD

≤ 81.8/mm²

1.00

Reference

> 81.8/mm²

0.60

0.26-1.38

0.228

PSMA LI

≤ 48.3 %

1.00

Reference

> 49.3 %

1.84

0.81-4.20

0.147

hTERT LI

≤ 43.8 %

1.00

Reference

> 43.8 %

0.48

0.21-1.10

0.083