Variable

Univariate analysis

Multivariate analysis

RR

95% CI

p value*

RR

95% CI

p  value

Age (years)

≤ 67.0

1.00

Reference

> 67.0

1.59

0.52-4.86

0.416

PSA

≤ 10.2 ng/mL

1.00

Reference

> 10.2 ng/mL

1.32

1.22-11.47

0.020

AJCC Grade

1-3

1.00

Reference

4-5

3.83

1.05-13.97

0.041

Clinical stage

cT1-2

1.00

Reference

0.051

cT3-4

3.04

0.99-9.30

Pathological stage

pT1-2

1.00

Reference

pT3-4

3.08

1.01-9.43

0.048

Radical surgery

yes

0.57

0.19-1.68

0.307

no

1.00

Reference

Hist-pat surgical margins

negative

1.00

Reference

positive

1.06

0.36-3.17

0.910

Seminal vesicle(s) invasion

negative

1.00

Reference

0.010

1.00

Reference

0.007

positive

4.15

1.39-12.36

4.48

1.50 – 13.34

Adjuvant treatment

no

1.00

Reference

yes

2.20

0.7-6.7

0.165

Ki-67LI

≤ 18.0 %

1.00

Reference

> 18.0 %

4.84

1.33-17.8

0.017

GLUT-1LI

≤ 19.1 %

1.00

Reference

> 19.1 %

2.40

0.66-8.71

0.183

VEGF LI

≤ 11.0 %

1.00

Reference

> 11.0 %

0.47

0.14-1.52

0.209

MVD

≤ 94.2/mm²

1.00

Reference

> 94.2/mm²

1.10

0.34-3.57

0.876

PSMA LI

≤ 76.7 %

1.00

Reference

> 76.7 %

2.72

0.60-12.30

0.193

hTERT LI

≤ 43.8 %

1.00

Reference

1.00

Reference

> 43.8 %

0.23

0.07-0.75

0.015

0.22

0.07-0.71

0.011