Table 4: Cox univariate analysis of the biological and clinicopathological features of prostate cancer predicting Local recurrence-free survival in localized PCa patients.

Variable

Univariate analysis

RR

95% CI

p value*

Age (years)

 

 

 

≤ 71.0

1.00

Reference

 

> 71.0

1.85

0.40-8.48

0.426

PSA

 

 

 

≤ 7.7 ng/mL

1.00

Reference

 

> 7.7 ng/mL

4.32

0.95-19.75

0.06

AJCC Grade

 

 

 

1-3

1.00

Reference

 

4-5

1.05

0.14-8.20

0.957

Clinical stage

 

 

 

cT1-2

1.00

Reference

0.715

cT3-4

1.23

0.39-3.91

 

Pathological stage

 

 

 

pT1-2

1.00

Reference

 

pT3-4

2.55

0.56-11.6

0.228

Radical surgery

 

 

 

yes

0.49

0.15-1.53

0.222

no

1.00

Reference

 

Hist-pat surgical margins

 

 

 

negative

0.75

0.26-2.61

0.748

positive

1.00

Reference

 

Seminal vesicle(s) invasion

 

 

 

negative

1.00

Reference

 

positive

1.49

0.41-5.53

0.546

Adjuvant treatment

 

 

 

no

1.00

Reference

 

yes

4.17

1.12-15.4

0.032

Ki-67LI

 

 

 

≤ 9.2 %

1.00

Reference

 

> 9.2 %

2.87

0.93-8.91

0.07

GLUT-1LI

 

 

 

≤ 16.0 %

1.00

Reference

 

> 16.0 %

1.94

0.53-7.2

0.316

VEGF LI

 

 

 

≤ 4.3 %

1.00

Reference

 

> 4.3 %

0.79

0.25-2.49

0.689

MVD

 

 

 

≤ 77.2/mm2

1.00

Reference

 

> 77.2/mm2

0.38

0.12-1.20

0.100

PSMA LI

 

 

 

≤ 53.3 %

1.00

Reference

 

> 53.3 %

1.73

0.56-5.37

0.342

hTERT LI

 

 

 

≤ 14.0 %

1.00

Reference

 

> 14.0 %

0.37

0.08-1.69

0.198

RR: risk ratio, CI: confidence interval.