Baseline characteristics

No. of patients (%), N=28

Age

  Mean (range)

49 y (33-61)

Sex

  Male/Female

21 (75%) / 7 (25%)

ECOG

  0

  1

  2

10 (35.7%)

17 (60.7%)

1 (3.57%)

Histology

  Keratinized, squamous

  Non-keratinized squamous

  Undifferentiated

1 (3.57%)

1 (3.57%)

26 (92.9%)

T category

  1

  2

  3

  4

2 (7.14%)

2 (7.14%)

7 (25%)

17 (60.7%)

N category

  0

  1

  2

  3

3 (10.7%)

9 (32.1%)

4 (14.3%)

12 (42.9%)

Radiation dose

  70 Gy

  30 Gy (palliative dose)

27 (96.4%)

1 (3.57%)

Baseline EBV DNA

  Mean (range)

3683 copies/ml (0-28750)

Post radical RT

No of patients (%), N=27

6 weeks post-treatment NP biopsy

  No residue

  Residue

26 (96.2%)

1 (3.7%)

8 weeks post-treatment EBV DNA

  0 copy

  >0 copy

  Missing data

24 (88.9%)

3 (11.1%)

0

26 weeks post-treatment EBV DNA

  0 copy

  >0 copy

  Missing data

23 (85.2%)

2 (7.4%)

2 (7.4%)

16 weeks post-treatment MRI or PET

  Complete remission

  Partial response

  Missing data

26 (96.2%)

1 (3.7%)

0

Median follow up

  Median (range)

2 years (8.6-39.5 months)