Treatment

Initial paw reading

30mins

1hr

2hr

3hr

4h

Control (1ml)

4.18±0.08

8.52 ±0.36

8.45            0.37

8.42 ±0.37

8.06 ±0.32

7.46 ±0.20

Indomethacin(10mg/kg)

4.08±0.15

5.19 ±0.07

5.13 ±0.06

5.5±0.05

4.64 ±0.02

4.41 ±0.03

Organic extract(200mg/kg)

3.86±0.47

7.38 ±0.19

7.02

0.05*

6.88 ±0.05*

5.93 ±0.01*

5.82 ±0.01*

Organic extract(400mg/kg)

3.82±0.13

7.31 ±0.22

7.13 ±0.16*

7.00 ±0.16*

5.63 ±0.23*

4.34

0.30*#

Aqueous extract(200mg/kg)

4.15±0.04

6.55 ±0.21

6.47 ±0.24

6.37 ±0.19*

6.06 ±0.04*

5.71 ±0.05*

Aqueous extract(400mg/kg)

3.98±0.07

7.94 ±0.03

7.37 ±0.09*

7.26 ±0.10*

6.07 ±0.12*

5.35 ±0.19*

n-hexane fraction(200mg/kg)

4.11±0.05

8.25 ± 0.14

8.11 ±0.14

8.06 ±0.13*

7.36 ±0.32*

5.84 ±0.33*

n-hexane fraction(400mg/kg)

3.56±0.21

7.43 ±0.31

7.27 ±0.36

7.16 ±0.35*

5.85 ±0.14*

4.95 ±0.03*

Ethylacetate fraction(200mg/kg)

4.53±0.24

8.20 ±0.24

7.95 ±0.12*

7.85 ±0.12*

6.77 ±0.11*

5.90 ±0.06*

Ethylacectate fraction(400mg/kg)

3.67±0.15

8.08 ±0.12

7.60 ±0.35*

7.40 ±0.42*

5.79 ±0.39*

4.15

0.28*#

n-butanol fraction(200mg/kg)

3.88±0.09

8.08 ±0.21

8.00 ±0.23*

7.89 ±0.25*

7.00 ±0.04*

5.61 ±0.14*

n-butanol fraction(400mg/kg)

3.58±0.29

7.75 ±0.36

7.63 ±0.31*

7.41 ±0.25*

5.97 ±0.14*

4.00

0.19*#

Aqueous fraction(200mg/kg)

4.28±0.06

8.57 ±0.22

8.50 ±0.20

8.20 ±0.18*

7.56 ±0.28*

6.37 ±0.27*

Aqueous fraction(400mg/kg)

3.77±0.09

7.97 ±0.04

7.35 ±0.25*

7.13 ±0.24*

6.13 ±0.23*

5.17 ±0.15*