Parameters

Case no.

PD-L1 expression (CPS)

Resection

PD-L1 expression (CPS)

Biopsy

CPS≥1

CPS<1

P-value

CPS≥1

CPS<1

P-value

Gender

Male

Female

31

8

26 (83.9%)

7 (87.5%)

5 (16.1%)

1 (12.5%)

0.8

10 (32.3%)

0 (0%)

21 (67.7%)

8 (100.0%)

0.06

Mean age (range)

57.8

(30-74)

62.2

(59-80)

58.1

(44-70)

58.7

(30-80)

AJCC Stage

I/II

III/IV

14

25

12 (85.7%)

21 (84.0%)

2 (14.3%)

4 (16.0%)

0.89

4 (28.6%)

6 (24.0%)

10 (71.4%)

19 (76.0%)

0.75

T Stage

T2

T3

T4a

T4b

3

17

18

1

2 (66.7%)

14 (85.7%)

16 (84.0%)

1 (100.0%)

1 (33.3%)

3 (14.3%)

2 (16.0%)

0 (0%)

0.74

1 (33.3%)

3 (28.6%)

6 (33.3%)

0 (0%)

2 (66.7%)

14 (71.4%)

12 (66.7%)

1 (100.0%)

0.67

N Stage

N0

N1

N2

N3a

N3b

5

11

9

4

10

4 (80.0%)

8 (72.7%)

9 (100.0%)

4 (100.0%)

8 (80.0 %)

1 (20.0%)

3 (27.3%)

0 (0%)

0 (0%)

2 (20.0 %)

0.43

2 (40.0%)

3 (27.3%)

2 (22.2%)

1 (25.0%)

2 (20.0%)

3 (60.0%)

8 (72.7%)

7 (77.8%)

3 (75.0%)

8 (80.0%)

0.94

Dukes-MAC like stage

B2

C1

C2

D

4

2

14

19

3 (75.0%)

1 (50.0%)

12 (85.7%)

17 (89.5 %)

1 (25.0%)

1 (50.0%)

2 (14.3%)

2 (10.5 %)

0.48

1 (75.0%)

1 (50.0%)

2 (14.3%)

6 (31.6%)

3 (25.0%)

1 (50.0%)

12 (85.7%)

13 (68.4%)

0.59

WHO classification

WD/MD

PD/UND

SRRC

GCLS

10

26

2

1

9 (90.0%)

23 (88.5%)

0 (0%)

1 (100.0%)

1 (10.0%)

3 (11.5%)

2(100.0%)

0 (0%)

0.01

3 (30.0%)

7 (27.0%)

0 (0%)

0 (0%)

7 (70.0%)

19 (73.0%)

2 (100.0%)

1 (100.0%)

0.67

EBV

 Positive

 Negative

MSI

 MSI-H

 MSS/MSI-L

4

35

4

35

4 (100.0%)

29 (82.9%)

4 (100.0%)

29 (82.9%)

0 (0%)

6 (17.1%)

0 (0%)

6 (17.1%)

1.00

1.00

2 (50%)

8 (22.9%)

4 (100.0%)

6 (17.1%)

2 (50%)

27 (77.1%)

0 (0%)

29 (82.9%)

0.27

0.003

Total

39

33 (84.6%)

6 (15.4%)

29 (74.4%)

10 (25.6%)