Table 4:  Initial treatment for patients with invasive cancer (including in situ bladder) diagnosed during the successive eras 1989-1995 and 1996-2003.

Treatment

1989-1995

% of 7,662 patients

1996-2003

% of 12,977 patients

P value

Chi Sq

Surgery only

33.5

30.5

<.0001

Surgery + radiation

8.2

7.1

.0034

Radiation only

7.2

6.8

.27

Systemic therapy only*

17.8

16.6

.026

Surgery + systemic therapy

11.8

10.6

.0081

Radiation + systemic

0.6

2.1

<.0001

Surgery, radiation & systemic

9.6

13.7

<.0001

Received any systemic therapy

39.8

43.0

<.0001

No anti-cancer therapy

11.3

12.5

.011

* chemotherapy, hormonal therapy, biological response modifier (BRM)