Table 2: Univariate comparison between responders and non-responders.

Clinical and disease-related features

Responders (TRS 0-2)

Non-responders

(TRS 3)

P-value

N = 34 (47.2%)

N = 38 (52.8%)

Gender

Male

22 (64.7%)

22 (57.9%)

0.554

Female

12 (35.3%)

16 (42.1%)

Mean age (years)

 

63.08 ± 13.87

63.18 ± 11.44

0.668

Pre-operative staging

Stage 1

1 (2.9%)

0 (0%)

0.894

Stage 2

16 (47.1%)

19 (50%)

Stage 3

17 (50%)

19 (50%)

Radiotherapy

Short course

3 (8.8%)

4 (10.5%)

0.808

Long course

31 (91.2%)

34 (89.5%)

Surgical approach

Lap (intent to treat)

23 (67.7%)

25 (65.8%)

0.86

Open

11 (32.3%)

13 (34.2%)

0.86

Lap converted to open

1 (2.9%)

8 (21%)

0.02

Post-operative staging

Stage 0

12 (35.3%)

0 (0%)

0.0001 

Stage 1

9 (26.5%)

11 (28.9%)

0.815

Stage 2

8 (23.5%)

17 (44.7%)

0.059

Stage 3

5 (14.7%)

10 (26.3%)

0.226

Adjuvant chemotherapy

Yes

12 (35.3%)

19 (50%)

0.208

No

22 (64.7%)

19 (50%)

Mean follow-up (months)

 

59.97 ± 48.70

58.76 ± 36.76

0.914