Table 5: Immunohistochemistry analysis of biopsy samples (n=9).hENT1: Human equilibrative nucleoside transporter 1; RRM: Ribonucleotide reductase subunit M; TK1: Thymidine kinase 1; HUR: human antigen R; Ki67: protein Ki-67.
|
No Expression |
Mild Expression |
Moderate Expression |
High Expression |
Benefit prediction of gemcitabine-based chemotherapy (logistic regression) p-value) |
|
|
hENT1 |
1 (11.1%) |
3 (33.3%) |
4 (44.4%) |
1 (11.1%) |
0.438 |
|
RRM |
1 (11.1%) |
6 (66.7%) |
2 (22.2%) |
0 (0%) |
0.399 |
|
TK1 |
0 (0%) |
3 (33.3%) |
2 (22.2%) |
4 (44.4%) |
0.181 |
|
HUR |
0 (0%) |
1 (11.1%) |
3 (33.3%) |
5 (55.6%) |
- |
|
Ki67 Median (95%CI) (range) |
15 (10-20) (5-70) |
- |
- |
- |
- |