Table 4: PMN Functions in untreated patients with solid tumors. The chemotaxis numbers present the average number of migrated PMN per high-power field after counting 20 high-power fields ± standard deviation. The percentage of ingested Candida albicans that were killed after 2 hrs incubation with PMN was calculated by determining the viability of 200 intracellular yeast particles. The mean number of phagocytosed yeast particles per 100 PMN is presented ± standard deviation.
|
Subjects |
Number |
Chemotaxis |
% Intracellular killing of Candida albicans |
% Phagocytosis of Candida albicans |
|
All Head and Neck cancer patients |
33 |
112.0 ± 33.7a |
14.8 ± 2.39 |
|
|
Initial diagnosed Head and Neck cancer patients |
8 |
96.7 ± 31.3a |
|
|
|
Other solid cancer patients |
13 |
129.0 ± 30.4 |
10.6 ± 3.84a |
|
|
All Cancer patients |
46 |
116.0 ± 33.1a |
13.3 ± 3.5 |
67.0 ± 14.3 |
|
Healthy controls |
45 |
131.4 ±18.2 |
15.8 ± 7.6 |
66.4 ±13.5 |
ap<0.02 based on paired t-test with healthy controls tested at the same time.