Table 1: Plasma AVP and Inflammatory Biomarkers
|
Overall |
CRP |
IL-2 |
IL-4 |
IL-6 |
IL-8 |
IL-10 |
IFNG |
TNF-a |
IL-1a |
IL-1b |
VEGF |
|
|
Baseline AVP |
Pearson Correlation |
-0.189 |
-0.031 |
-0.053 |
0.224 |
0.244 |
0.158 |
-0.046 |
-0.063 |
0.068 |
-0.001 |
-0.051 |
|
Sig. (2-tailed) |
0.300 |
0.868 |
0.788 |
0.219 |
0.178 |
0.430 |
0.805 |
0.732 |
0.730 |
0.996 |
0.786 |
|
|
N |
32 |
32 |
28 |
32 |
32 |
27 |
31 |
32 |
28 |
26 |
31 |
|
|
|
||||||||||||
|
Low AVP Group |
CRP |
IL-2 |
IL-4 |
IL-6 |
IL-8 |
IL-10 |
IFNG |
TNF-a |
IL-1a |
IL-1b |
VEGF |
|
|
Baseline AVP |
Pearson Correlation |
0.373 |
-0.040 |
0.358 |
0.151 |
0.215 |
-0.554 |
0.036 |
-0.217 |
0.430 |
0.169 |
-0.116 |
|
Sig. (2-tailed) |
0.154 |
0.884 |
0.190 |
0.578 |
0.425 |
0.032* |
0.896 |
0.419 |
0.110 |
0.564 |
0.668 |
|
|
N |
16 |
16 |
15 |
16 |
16 |
15 |
16 |
16 |
15 |
14 |
16 |
|
|
|
||||||||||||
|
High AVP Group |
CRP |
IL-2 |
IL-4 |
IL-6 |
IL-8 |
IL-10 |
IFNG |
TNF-a |
IL-1a |
IL-1b |
VEGF |
|
|
BaselineAVP |
Pearson Correlation |
-0.370 |
-0.255 |
-0.256 |
0.232 |
0.162 |
0.046 |
-0.209 |
-0.250 |
-0.274 |
-0.255 |
-0.210 |
|
Sig. (2-tailed) |
0.158 |
0.340 |
0.398 |
0.387 |
0.549 |
0.887 |
0.455 |
0.350 |
0.364 |
0.424 |
0.453 |
|
|
N |
16 |
16 |
13 |
16 |
16 |
12 |
15 |
16 |
13 |
12 |
15 |
|
Legend: Inflammatory biomarkers were measured from patient blood samples and subsequently compared to baseline AVP levels. No significant relationship was found between any inflammatory biomarker and baseline AVP levels upon overall comparison of values. After a median-split separation of AVP into low AVP and high AVP subgroups, a significant negative correlation (p=0.032) was found between IL-10 and baseline AVP within the low AVP subgroup.