Table 1: Manchester criteria for clinical diagnosis of NF2.

 

Additional findings needed for diagnosis

Bilateral vestibular schwannomas

None

1st degree family relative with NF2

Unilateral vestibular schwannoma or two NF2-associated lesions (meningioma, glioma, neurofibroma, schwannoma, or cataract)

Unilateral vestibular schwannoma

Two NF2-associated lesions associated with the disorder (meningioma, glioma, neurofibroma, schwannoma, or cataract)

Multiple meningiomas

Unilateral vestibular schwannoma or two other NF2-associated lesions (glioma, neurofibromas, schwannoma, or cataract)