Complications and Cure Rates of Parathyroidectomy for Primary Hyperparathyroidism with Negative Localization Studies

Complications and Cure Rates of Parathyroidectomy for Primary Hyperparathyroidism with Negative Localization Studies

Author Info

Corresponding Author
Bassam Abboud
Division of General Surgery, Faculty of Medicine, Geitaoui Hospital, Lebanese University, Beirut, Lebanon

A B S T R A C T

Purpose: This paper evaluates the outcomes of parathyroidectomy for primary hyperparathyroidism with negative localization studies. Methods: All patients with primary hyperparathyroidism with negative preoperative ultrasound and MIBI scan who underwent parathyroidectomy were retrospectively included. Three groups were defined. Group 1 included the patients with negative ultrasound and MIBI. Group 2 included the patients with negative ultrasound and positive MIBI. Group 3 included the patients with positive ultrasound and negative MIBI. Results: In Group 1, 51% and 86% of patients had one adenoma and atypical localizations respectively. Unique adenoma and atypical localizations were showed in 87% and 93% of patients in Group 2 respectively. In Group 3, 83% and 17% of patients had one adenoma and atypical localizations respectively. No cervical hematoma was noted. Transient recurrent laryngeal nerve palsy occurred in 2 patients. Seven patients required postoperative calcium supplementation for 2 to 5 months, and one had recurrent hypercalcemia at follow-up. Cure rate was 98,3%. Conclusion: When US and MIBI were negative, multiple lesions and atypical localizations were frequent. The success rate and postoperative complications were not affected with this event.

Article Info

Article Type
Research Article
Publication history
Received: Mon 07, Dec 2020
Accepted: Mon 25, Jan 2021
Published: Sat 30, Jan 2021
Copyright
© 2021 Bassam Abboud. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository. All rights reserved.
DOI: 10.31487/j.SCR.2021.01.19