Utility of Intraoperative Cortico-Cortical Evoked Potentials for the Evaluation of Language Function During Brain Tumor Resection

Utility of Intraoperative Cortico-Cortical Evoked Potentials for the Evaluation of Language Function During Brain Tumor Resection

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Corresponding Author
Jesús Pastor Gómez
Clinical Neurophysiology, Hospital Universitario de la Princesa, Madrid, Spain

A B S T R A C T

The cortico-cortical evoked potentials (CCEP) are a relatively recent intraoperative monitoring tool that has shown high reliability in detecting the functional language area and its connections. In this work we describe a patient with a tumor located in the language area who underwent tumor resection. A neurophysiological intraoperative mapping of the frontal and posterior language area with the anesthetized patient was carried out. Then the patient was awaked. To demonstrate the relationship between language function and CCEP, the Ojemann’s stimulation technique was used in the same electrodes were CCEPs were obtained. An alteration in the emission of language had been found on the electrodes where CCEP was obtained and in adjacent electrodes. During tumor resection we used a double check for language function: neurological evaluation and CCEPs. We obtained a biunivocal relationship between warning criteria in the CCEP and immediate language impairment on neurological examination. We always observed a significant decrease in the CCEP associated with language impairment. The CCEP are able to obtain information in real time with a good spatial resolution of the language function. Future studies should be carried out in order to analyse the robustness of this technique to perform it in anesthetized patients.

Article Info

Article Type
Case Report
Publication history
Received: Mon 09, Nov 2020
Accepted: Fri 20, Nov 2020
Published: Thu 10, Dec 2020
Copyright
© 2021 Jesús Pastor Gómez. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository. All rights reserved.
DOI: 10.31487/j.SCR.2020.12.09