Pattern of Cardiovascular Risk Factors and Outcomes of Patients Older Than 80 Years and Presenting with Acute Coronary Syndromes

Pattern of Cardiovascular Risk Factors and Outcomes of Patients Older Than 80 Years and Presenting with Acute Coronary Syndromes

Author Info

Corresponding Author
Ahmed Mahmoud El Amrawy
Faculty of Medicine, Cardiology Department, Alexandria University, Egypt

A B S T R A C T

Objective: Elderly patients presenting with acute coronary syndrome (ACS) are at higher risk for morbidity, complications and early mortality than younger patients. Elderly are frequently underrepresented in clinical trials. Methods: A descriptive multi-center study including 760 patients admitted with ACS aiming to determine the most frequently encountered cardiovascular risk factors, as well as the in-hospital complications. Results: Of the 760 patients, 42.1% were males with a mean age of 85 years. Non-ST-elevation ACS was encountered in 496 patients (65.3%; NSTEMI 50% and unstable angina 15.3%) while STEMI was encountered in 264 patients (34.7%). Regarding risk factors, 61.1% of patients were hypertensive, 60% were diabetics, 44.7% were smokers, 28.9% had dyslipidemia, 16.8% had a family history of coronary artery disease, and 20% had chronic renal impairment at presentation. 252 patients (33.2%) underwent primary PCI, 440 patients (57.9%) underwent elective PCI, 36 patients (4.7%) underwent coronary artery bypass graft (CABG) surgery while 32 patients (4.2%) were maintained on conservative medical therapy and no patients received fibrinolytic therapy. In-hospital mortality was only 3.7% (28 patients), Cerebrovascular stroke occurred in 16 patients (2.1%) and recurrent infarction occurred only in 8 patients (1.1%). Conclusion: In patients over 80 years presenting with ACS, female sex, hypertension and diabetes were the most frequently encountered cardiovascular risk factors, with more frequent presentation of NSTEMI than STEMI and in-hospital mortality of 3.7%.

Article Info

Article Type
Research Article
Publication history
Received: Wed 30, Dec 2020
Accepted: Thu 18, Feb 2021
Published: Fri 05, Mar 2021
Copyright
© 2023 Ahmed Mahmoud El Amrawy. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.JICOA.2021.01.11