Psoriasis as the single risk factor for “Locked-in syndrome” after ischemic stroke in a young patient: Case Report and Literature Review

Psoriasis as the single risk factor for “Locked-in syndrome” after ischemic stroke in a young patient: Case Report and Literature Review

Author Info

Corresponding Author
Mahesh Krishnamurthy
Easton Hospital, Easton, PA, USA

A B S T R A C T

Background: Locked-in syndrome (LIS), also known as cerebromedullospinal disconnection or pseudocoma, is a rare neurological disorder. LIS is most commonly caused by ischemic or hemorrhagic pontine stroke. Autoimmune diseases have been shown to increase risk of cardiovascular disease and cerebrovascular disease. Psoriasis as an isolated risk factor for LIS has not been described in literature Case Description: A 50-year-old male patient with psoriasis and no other obvious risk factors presented to the ER after being found in his home with loss of consciousness. He was diagnosed with basilar artery thrombosis and pontine stroke which lead to post-stroke LIS. Conclusion: Most patients seek treatment for psoriasis from a cosmetic perspective. It is important to stress the cardiovascular and cerebrovascular risks associated with untreated psoriasis to patients who refuse treatment. Our patient with locked-in syndrome makes this teaching point emphatically.

Article Info

Article Type
Case Report & Literature Review
Publication history
Received: Thu 03, Jan 2019
Accepted: Wed 16, Jan 2019
Published: Sat 26, Jan 2019
Copyright
© 2023 Mahesh Krishnamurthy. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.JICOA.2019.01.002