Evidence of Dental Lamina Preservation in the Development of Mice First Molars

Evidence of Dental Lamina Preservation in the Development of Mice First Molars

Author Info

Corresponding Author
Hermes Pretel
Department of Restorative Dentistry, Araraquara School of Dentistry, São Paulo State University - Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Araraquara, São Paulo, Brazil


The aim of this work was to analyse the behaviour of the dental lamina during the development process of first molar teeth. The offspring of female mice were analysed at the 16th day of intra-uterine life and since birth till 17 days old with the aim to evaluate the dental lamina evolution of upper and lower first molars. The animals were sacrificed, and the heads embedded in paraffin in order to get frontal or sagittal sections whose were stained by hematoxylin and eosin method. The results showed a very clear presence of the dental lamina in all periods under analysis, without the occurrence of its disorganization, in other words, it was permanently connecting the developing tooth germ to the oral epithelium until advanced dental eruption.

Article Info

Article Type
Research Article
Publication history
Received: Fri 18, Dec 2020
Accepted: Sat 09, Jan 2021
Published: Fri 15, Jan 2021
© 2021 Hermes Pretel. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository. All rights reserved.
DOI: 10.31487/j.DOBCR.2021.01.01