Pulmonary Mucosa-Associated Lymphoid Tissue Lymphoma- A Single Center Review of the Diagnostic Approach

Pulmonary Mucosa-Associated Lymphoid Tissue Lymphoma- A Single Center Review of the Diagnostic Approach

Author Info

Corresponding Author
Aisling Farrell
Department of Respiratory Medicine and Regional Lung Cancer service, Cork University Hospital, Cork, Republic of Ireland

A B S T R A C T

Pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma is a rare disease, and diagnosis is difficult, often requiring multiple attempts at tissue sampling. The aim of this review was to evaluate the diagnostic pathway. A retrospective review was performed of patients diagnosed with pulmonary MALT lymphoma in a tertiary referral lung cancer center over 9 years. Ten patients were identified, and each diagnostic and treatment approach was analysed. 30% were diagnosed via transbronchial biopsy, two with the assistance of radial probe ultrasound guidance and one with transbronchial lung cryobiopsy of a predetermined CT-guided targeted segment. 70% were diagnosed following surgical biopsy. 40% had localized disease. The diagnosis was not successfully achieved until a large-sized tissue specimen was obtained. The implementation of novel bronchoscopy techniques can assist in reducing the number of invasive surgical procedures required to obtain a diagnosis. All cases should be discussed in a multidisciplinary setting prior to diagnostic attempts.

Article Info

Article Type
Review Article
Publication history
Received: Wed 13, May 2020
Accepted: Wed 03, Jun 2020
Published: Fri 12, Jun 2020
Copyright
© 2023 Aisling Farrell. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.COR.2020.06.06