Primary Thyroid Lymphoma in an Adolescent with Hashimoto’s Thyroiditis and Congenital Deafness

Author Info

Jaques van Heerden Joris Verlooy Koen Norga Thomas Tousseyn Yeleni Eelen

Corresponding Author

Yeleni Eelen
Department of Paediatrics, Antwerp University Hospital, University of Antwerp, Belgium

A B S T R A C T

Background: Primary thyroid lymphoma is extremely rare in children and adolescents. The diagnosis of thyroid malignancies is often made secondary to other thyroid pathologies including Hashimoto’s thyroiditis (HT). Case Presentation: This case describes a 14-year-old girl with a background of HT and congenital deafness that presented with a rapidly enlarging multinodular thyroid mass. She underwent a total thyroidectomy and a diffuse, large B-cell lymphoma was diagnosed on pathology. Discussion: Primary thyroid disease is an extremely rare disease in childhood, usually presenting as a rapidly enlarging goitre. The correlation between Hashimoto’s thyroiditis and primary thyroid lymphoma is well-established in adults but has not been verified in the paediatric population. Our patient also has βthalassemia and Usher syndrome, however, no correlation between these and primary thyroid lymphoma could be found in the literature. Conclusion: It is important to include malignancy in the differential diagnosis of thyroid enlargement or unexplained symptoms, especially in the presence of syndromes. Further research into the relation between lymphomas and HT in the paediatric population is needed.

Article Info

Article Type

Case Report

Publication history

Received: Wed 06, May 2020
Accepted: Mon 18, May 2020
Published: Fri 29, May 2020

Copyright

© 2023 Yeleni Eelen. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.COR.2020.05.11