ABO, H, Lewis and Secretor histo-blood group-like carbohydrates in pathogenic and non-pathogenic invertebrates
Corresponding AuthorLuiz Carlos de Mattos
Laboratório de Imunogenética, Departamento de Biologia Molecular, Faculdade de Medicina de São José do Rio Preto - FAMERP
A B S T R A C T
ABO, H, Lewis, and Secretor histo-blood group systems express a repertoire of carbohydrate antigens in human hematopoietic and non-hematopoietic tissues. The oligosaccharide components of these systems are widely distributed in nature, including animal and plants. A set of reports demonstrated that pathogenic and non-pathogenic invertebrates are able to synthesize and or acquire histo-blood group-like carbohydrates from hosts. These abilities seem to be related to strategies for cell invasion as well as scape from host’s innate and adaptive immune responses. This text revised the literature and offers a tentative explanation for the presence of histo-blood group-like carbohydrates in pathogenic and non-pathogenic invertebrates and its importance in terms of evolution.
Article TypeResearch Article
Publication historyReceived: Wed 17, Apr 2019
Accepted: Fri 19, Jul 2019
Published: Thu 08, Aug 2019
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